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Sobrinho LG, Duarte JS, Paiva I, Gomes L, Vicente V, Aguiar P.
, Paternal deprivation prior to adolescence and vulnerability to pituitary adenomas., GETH & Keypoint, Pituitary. 2011 Jun 24., 2011/10/10
It has been reported that women with prolactinoma were exposed, early in life, to an environment characterized by an absent or violent father. The present study was designed to evaluate whether paternal absence or violent paternal behavior were more prevalent in patients with pituitary adenomas (prolactinoma, acromegaly, non-secreting adenoma and Cushing's disease) compared to a control population. We conducted an observational case-control multicenter study. We interviewed 395 patients with prolactinoma (296 females and 99 males), 130 with acromegaly (87 females and 43 males), 237 with non-secreting adenoma (144 females and 93 males) and 68 with Cushing's disease (61 females and 7 males) and 365 patients from the same clinics with nodular thyroid disease or lymphocytic thyroiditis with euthyroidism as controls. Violent or absent fathers were significantly more prevalent in patients with prolactinoma or acromegaly than in controls (P = 0.001 and P = 0.002, respectively) but not in patients with non-secreting adenoma or corticotrophinoma. Absent fathers in prolactinoma and acromegaly versus controls: P = 0.001 and P = 0.119. Violent fathers in prolactinoma and acromegaly versus controls: P = 0.069 and P = 0.001. The prevalence of absent or violent fathers was also significantly higher in prolactinoma and acromegaly when compared to non-secreting adenoma (P = 0.039 and P = 0.033, respectively). Paternal deprivation before adolescence may be a risk factor for prolactinoma and acromegaly but not for non-secreting pituitary adenomas or Cushing's disease. Procedimentos_Invasivos_recomendacoes_GETNE.pdf MJ Bugalho1, JM Lopes2, Ana P Santos3 e todos os membros do GE-TNE participantes., Tumores neuroendócrinos: preparação para procedimentos invasivos., 1Assistente Graduada de Endocrinologia do IPO de Lisboa, Professora Auxiliar Convidada da Faculdade de Ciências Médicas de Lisboa, secretária do GE-TNE, 2Professor Associado de Anatomia Patológica da Faculdade de Medicina do Porto, Chefe de Serviço de Anatomia Patológica do Hospital de São João, Investigador Sénior do Instituto de Patologia e Imunologia Molecular da Universidade do Porto (IPATIMUP), secretário do GE-TNE 3Assistente Graduada de Endocrinologia do IPO-Porto, Coordenadora do GE-TNE., Rev P Endo D Metabol JUL_DEZ2010, 2011/07/02 A elaboração de normas para adequada preparação de doentes com Tumores Neuroendócrinos (TNEs) e indicação cirúrgica ou propostos para outros procedimentos invasivos (por exemplo: embolização arterial, ablação por radiofrequência e procedimentos endoscópicos) partiu de uma proposta que foi amplamente discutida dando origem ao documento que agora se divulga e que sumariza os consensos mínimos. Limbert E, Prazeres S, São Pedro M, Madureira D, Miranda A, Ribeiro M, Jacome de Castro J, Carrilho F, Oliveira MJ, Reguengo H, Borges F; Thyroid Study Group of the Portuguese Endocrine Society., Iodine intake in Portuguese pregnant women: results of a countrywide study., Pode aceder ao artigo em texto integral em http://eje-online.org/content/163/4/631.long#ref-list-1, Eur J Endocrinol. 2010 Oct;163(4, 2010/11/10
BACKGROUND:
Iodine is the key element for thyroid hormone synthesis, and its deficiency, even moderate, is harmful in pregnancy, when needs are increased, because of its potential deleterious effects on fetal brain development. In Portugal, no recent data on iodine intake exists. The objective of this countrywide study was to analyze iodine status in pregnant Portuguese women in order to propose adequate measures to the health authorities.
SUBJECTS AND METHODS:
Using a fast colorimetric method, urine iodine concentration (UIC) was evaluated in 3631 pregnant women followed in 17 maternity hospitals from hinterland and coastal areas in Continental Portugal and the Portuguese islands of Açores and Madeira.
RESULTS:
Median UIC value was 84.9 μg/l (range 67.6-124.1) in Continental Portugal, 69.5 μg/l in Madeira, and 50.0 μg/l in Açores. The percentage of satisfactory values (>150 μg/l) was 16.8, ranging from 8.8 to 34.1 in the Continent, and being 8.2 in Madeira and 2.3 in Açores. The percentage of values below 50 μg/l was 23.7, ranging from 14.0 to 37.4 in the Continent, 33.7 in Madeira, and 50.0 in Açores.
CONCLUSIONS:
Our results point to an inadequate iodine intake in pregnant women assisted in most Portuguese maternity hospitals. Considering the potential deleterious effects of inadequate iodine supply in pregnancy, iodine supplementation is strongly recommended in this period of life. Citopatologia.jpg Ali, Syed Z.; Cibas, Edmund S. (Eds.), Leitura recomendada: The Bethesda System for Reporting Thyroid Cytopathology, © Springer, ISBN: 978-0-387-87665-8, 2010/02/01 A citologia aspirativa da tiroide por agulha fina é um dos procedimentos citológicos mais comumente realizados. É o método padrão de diagnóstico para a os doentes com nódulos da tiroide. Até agora, não houve nenhum sistema uniforme de apresentação dos resultados da citologia aspirativa por agulha fina da tireóide (FNA) em os E.U. A terminologia descrita neste livro é um importante avanço no campo da citopatologia. Ela representa os resultados da Conferência multidisciplinar do Instituto Nacional do Cancro de tiroide sobre o estado da arte da FNA, realizado em Bethesda, MD, em Outubro de 2007.
O Sistema Bethesda para relato da Citopatologia irá fornecer ao leitor uma abordagem unificada para diagnosticar e relatar as interpretações FNA da tireóide. Servirá como um guia de referência não apenas para os patologistas, mas também endocrinologistas, cirurgiões e radiologistas.
Escrito para:
Citopatologistas, patologistas clínicos e anatomistas /, estagiários e bolseiros em citopatologia e tecnicos de citopatologia
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